Choice? Bah! Humbug!
نویسنده
چکیده
منابع مشابه
Control not at initiation? Bah, humbug!
Initiation is often assumed to be rate-limiting for protein synthesis, but the presence of rare codons nonetheless can influence protein levels. In this issue of The EMBO Journal, Chu et al report that when rare codons are positioned near the start of the coding region, 'liberation' of the initiation codon for loading of the next 40S subunit may be rate‐limiting for initiation and therefore ove...
متن کاملOptimized Expression and Purification of Humbug in Pichia pastoris and Its Monoclonal Antibody Preparation
BACKGROUND The humbug gene is a truncated isoform of Aspartyl β-hydroxylase (ASPH) gene that is overexpressed in many human malignancies. In recent years, since humbug has received increasing attention, it is considered as a potential therapeutic molecular target. Therefore, it is necessary for preparing humbug protein and its monoclonal antibody to investigate its structure and function. MET...
متن کاملEvaluation of HAAH/humbug quantitative detection in the diagnosis of hepatocellular carcinoma.
Human aspartyl-(asparaginyl)-β-hydroxylase (HAAH) is a type 2 transmembrane protein and an α-ketoglutarate-dependent dioxygenase that can stereospecifically catalyze the post-translational hydroxylation reaction of β-carbon atoms of aspartic acid and asparagine residues present in epidermal growth factor-like domains of certain specific proteins. Humbug is a truncated isoform of aspartyl (aspar...
متن کاملBah humbug: Unexpected Christmas cards and the reciprocity norm.
The reciprocity norm refers to the expectation that people will help those who helped them. A well-known study revealed that the norm is strong with Christmas cards, with 20% of people reciprocating a Christmas card received from a stranger. I attempted to conceptually replicate and extend this effect. In Study 1, 755 participants received a Christmas card supposedly from a more- versus less-si...
متن کاملOverexpression of humbug promotes malignant progression in human gastric cancer cells.
Two human gastric cancer cell lines of differing invasive potential, SNU-484 and SNU-638 cells, were examined using subtractive suppression hybridization in a search for any genes associated with metastasis. Of the eight cDNAs identified as being differentially expressed genes, it was determined that humbug, which encodes a truncated isoform of aspartyl (asparaginyl) beta-hydroxylase (AAH) miss...
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عنوان ژورنال:
- Emergency medicine journal : EMJ
دوره 23 8 شماره
صفحات -
تاریخ انتشار 2006